In theory yes, you’ll have a slightly shorter wheel base. The smaller wheels will accelerate faster but have a slower top speed.
In my experience wheel size doesn’t make that big of a difference. I’ve skated on flat 72 chassis, rockered 72 on old Bauer h5 skates, and both 72-80 and 76-80 Hilo. The rocker setup improves mobility the most, less like being on skis as you mentioned. But only having 2 or 3 wheels in contact with the ground decreases stability too much for my liking.
I’m very interested in the marsblade r1 chassis so I have a set of those on pre-order, those should provide the solution to having some rocker while having all 4 wheels in contact with the ground.