If you want a forward pitch, I'd begin with the 25/45, see how you feel. Another option if you want more blade on the ice is to go Forward pitch for one holder size higher (25/45)
I prefer a lot of contact on the ice, and experimented, ended up on 280's, 35/65 CAG Profile. From what i experienced, most any appropriate CAG profiling felt better than stock steel profile, so you should notice it feeling better immediately.